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projects

mental health


Data Completeness.png Mental Health Project Image 2
correlation matrix alluvial plot
Early Detection & Intervention in Mental Health
shared with permission of Pandora Bio

Objectives: Pandora Bio is applying the principles of early cancer detection to the mental health space, with a focus on college students.

Contribution: The images shown are examples of my initial analysis of a longitudinal college student mental health data set collected by the Meet Pandora app. I consult with a team of data scientists, clinical statisticians, behavior scientists, and software engineers to develop mental health tools for early dectection and intervention. My contributions include feature pipeline maintenance and exploratory data analysis, building towards training and validation of predictive models. I also contribute to data goverance strategy.

Role: Data Science Consultant

oncology & bioinformatics


Liquid Biopsy Cancer Screening

Description: Product development and launch of an early cancer detection WGS-based liquid biopsy LDT product, with development towards FDA approval.

Contribution: Contributed to analysis pipeline productization, including feature engineering, QC development, ML model management and deployment, change management, and regulatory compliance, during pre-commercial through initial product launch and continued improvement. Oversaw development of internal data science software tooling.

Role: Full-time positions as Principal then Director of Data Science.

Precision Oncology

Description: Full-time position at a clinical stage company providing personalized tumor drug-susceptibility testing for cancer patients as an LDT.

Contribution: Oversaw continued development of the analysis and reporting pipeline, including change management, pipeline derisking, and introduction of software engineering best practices. Also worked with C-suite to systematize assay metrics and to develop and produce KPI reporting.

Role: Full-time position as Lead Bioinformatics Scientist.

RNA-seq-based Diagnostics

Description: Preclinical development of RNA-seq-based diagnostics for Alzheimers and lung cancer using an indicator cell assay.

Contribution: Continuous improvement and maintenance of RNA-seq analysis pipeline, including normalization, feature selection, and QC development. Improved diagnostic performance by 20%, helping to secure a $3M SBIR grant.

Role: Full-time position as Bioinformatics Scientist.

biomechanical and biochemical characterization
of biological specimen


Tissue Engineered Cartilage After Tribological Testing Tribological Trace Damage Detection
SVM Decision Boundary
Failure Mode Analysis of Tissue Engineered Cartilage

Objectives: To investigate how tissue culture conditions influence the tribological (frictional-shear) strength of engineered tissue constructs. Additionally, to develop a non-destructive method for detecting damage caused by tribological loading through an analysis of deviations in the coefficient of friction (CoF) over time—potentially eliminating the need for histological evaluation.

Approach: I utilized biphasic lubrication theory to model the expected CoF response under loading and evaluated this theoretical pattern compared to empirical CoF data. I then engineered features capturing deviations from the expected behavior, and used these features to train machine learning models to identify constructs exhibiting tribology-induced damage. Results from a support vector machine are shown.

real estate


MLS Data Mining

Description: Custom web application for evaluating real estate agent performance.

Contribution: Developed custom interactive Shiny App to analyze agent performance in table or graphical views. The app includes network graph visualizations of agent relationships, as well as performance metrics such as average days on market, list-to-sale price ratios, and transaction counts. The app allows users to filter by geography, time period, and other criteria to identify top-performing agents and trends in the local real estate market. Developed according to client specifications, with value-add features suggested during development.

Role: Consultant

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services


I offer a range of customized data science and machine learning services, including:

General Services
Machine Learning & Predictive Analytics
Software & Pipelines


Looking for help in other areas? Contact me to discuss your data science and machine learning needs.

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